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Nitrofurantoine

 

Chemical name:1-(5-nitrofurfurylideneamino)hydantoin
Structural formula:
Molecular formula:C8H6N4O5
Molecular weight:238.16
Property:It is yellow crystal powder,odorless ,bitter taste,it will turn dark in the light,it can absorb moisture and become nitrofurantoin.
Specification:
   A:Accord with China Pharmacopoeia 2010 edition
   Appearance:Yellow crystal powder
   Assay:98.0~102.0%
   Loss on drying:Not more than 1.0%
   Reidue on ignition:Not more than 0.1%
   Acidity:5.5~7.0
   Related substances :≤1%
   Nitrofurazone :≤ 0.01% 
   B:Accord with Europe Pharmacopoeia (EP6) edition 
   Appearance:A yellow crystalline powder or yellow crystals
   Assay:98.0~102.0%
   Loss on drying:Not more than 1.0%
   Sulphated ash:Not more than 0.1%
   Related substance: Not more than 1.0%
   C:Accord with United States Pharmacopoeia 32 edition 
   Appearance:A lemon-yellow crystalline powder . 
   Assay:98.0~102.0%
   Loss on drying:Not more than 1.0% 
   Limit of Nitrofurfural Diacetate:not more than 1.0%   
   Limit of Nitrofurazone:not more than 0.01%  
   Use: It is a antibacterial .

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